luteal cell การใช้

• Small luteal cells have LH receptors that regulate PKA activity within the cell.
• Progesterone is synthesized from cholesterol by both the large and small luteal cells upon luteal maturation.
• Cholesterol-LDL complexes bind to receptors on the plasma membrane of luteal cells and are internalized.
• It is secreted by luteal cells in the ovary and thus is important in the maturation of developing oocytes.
• Large luteal cells produce more progesterone due to uninhibited / basal levels of protein kinase A ( PKA ) activity within the cell.
• Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor in ovarian luteal cells initiates luteolysis and thus induces parturition.
• The follicular theca cells luteinize into small luteal cells ( thecal-lutein cells ) and follicular granulosa cells luteinize into large luteal cells ( granulosal-lutein cells ) forming the corpus luteum.
• The follicular theca cells luteinize into small luteal cells ( thecal-lutein cells ) and follicular granulosa cells luteinize into large luteal cells ( granulosal-lutein cells ) forming the corpus luteum.
• Osteonectin is expressed by a wide variety of cells, including chondrocytes, fibroblasts, platelets, endothelial cells, epithelial cells, Leydig cells, Sertoli cells, luteal cells, adrenal cortical cells, and numerous neoplastic cell lines ( such as SaOS-2 cells from human osteosarcoma ).
• Because P450scc and StAR are also essential for sex steroid synthesis in the testis and ovary, the production of testosterone by Leydig cells in the testis and androgen ( which leads to estrogen production by granulosa cells ) and progesterone by ovarian theca cells and luteal cells, respectively, can also be impaired.